Selecting The Best Ocean Freight Companies Is Easy

Selecting the best ocean freight companies is easy


palka madan12

Of course, you would want your product to make the best impression during the official overseas debut. Of course, you cannot get more excited about anything else. After researching on a huge number of ocean freight companies, you must decide on one that offers you best services at the best price. And yes, there is no better time to start than now!

First and foremost, you must get your things packed right away. There is a special technique to do this. Your product is quite small. Hence, you must pack it away in very small boxes. This also indicates that the company you choose palletize the product.

What is palletizing the product? When ocean freight forwarders palletize a product, they will take the small boxes you have prepared and place them on huge wooden pallets. Thereafter, they attach the product to the pallet via strapping it down. They might also shrink wrap the product. This creates good amount of space on the ship for more products. Additionally, your product will stay protected for the transportation across the ocean.

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Meanwhile you\’re putting your products in boxes; you must make sure these packed away in a safe manner in the boxes. You can also make use of newspaper, packing peanuts, or bubble wrap. This will depend on your preference.

You must guarantee that you hold the right labels on the boxes. These must also be carefully supplied to you via the freight transportation company that you have selected. They usually have your name and other important contact information, name of desired destination and complete address. The minute your product reaches across the ocean, the clients will require the label info to help your products get to the right place. The labels are of great help under circumstances where your product mixes up with another one.

Reaching out to the best

ocean freight companies

is important. This is how you can ensure best services at best prices. The

ocean freight forwarders

are widely offering services and each company claims to offer the best. Hence, it has become more important to choose your

freight transportation

with great care. Comparing and evaluating services and prices with great care is extremely important.

Reaching out to the best

ocean freight companies

is important. This is how you can ensure best services at best prices. The

ocean freight forwarders

are widely offering services and each company claims to offer the best. Hence, it has become more important to choose your

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Ukraine does not allow Transnistrian goods transit without Moldovan customs stamps

Tuesday, March 7, 2006

On March 3, Ukraine instituted a new customs regime at the border with Transnistria. Under the order issued by Ukrainian Customs’ head, at the request of President Viktor Yushchenko, all the Transnistrian goods that are transported via Ukraine will have to be accompanied by customs documents released by the Moldovan authorities.

Ukraine PM Yuri Yekhanurov has charged the Foreign Ministry and the State Customs officials to render the account to the society for the goods circulation on the Transdniestrian frontier. “In January I met the businessmen and authorities from Moldova, Ukraine and Transdniestrian in Odesa. In the course of the meeting the sides voiced their precise positions towards the rules of the game,” noted PM of Ukraine speaking about the special terms of freight transportation via the territory of Moldova, Ukraine and Transdniestrian region. According to his words, the freight from Transdniestrian region will cross Ukraine only if it has Moldova’s stamp. “It means no additional taxes or excise,” stressed PM Yekhanurov.

Javier SOLANA, EU High Representative for the CFSP, welcomes implementation by Moldova and Ukraine of Joint Declaration on Customs: “I welcome that the Joint Declaration of the Ukrainian and Moldovan Prime Ministers of 30 December 2005 is now being implemented, whereby Ukraine only recognizes Moldovan customs stamps and Moldova facilitates the registration of Transnistrian enterprises in Chisinau. The implementation of this declaration is very important for the establishment of an orderly regime on the Ukrainian-Moldovan border to which the EU attaches great importance.” Solana added also: “I call on the economic agents of the Transnistrian region of Moldova to register with the relevant authorities in Chisinau in order to promote the unimpeded flow of goods across the border. I also call on the self-proclaimed Transnistrian authorities not to block this registration. … I condemn any efforts by the self-proclaimed Transnistrian authorities to impede the free flow of international trade.”

The so-called Transnistrian president Igor Smirnov qualified Kiev’s decision as economic attack and called on the Ukrainian authorities to revise it so as to avert “a social-economic catastrophe” in the region.

Trade between Transnistria and Ukraine totals about US$400 million.

Finnish police isolate ports in Helsinki

Saturday, August 6, 2005

The Finnish police isolated the ports of Katajanokka and Länsisatama on Saturday. The ports were isolated at around 9.30 p.m. local time and the isolation was called off at around 11.30 p.m.

Finnish police received reports from Estonia that a shipping container loaded with explosives could be coming from Estonia Saturday evening. They checked every truck that passed the ports with the assistance of the Border Guard Service. There are still two ships due to arrive in Helsinki tonight, but they were already checked in Tallinn.

Vivien Goldman: An interview with the Punk Professor

Wednesday, October 3, 2007

Vivien Goldman recalls with a laugh the day in 1984 when she saw her death, but the laugh fades as she becomes lost in the memory. She was in Nigeria staying in Fela Kuti‘s home; she had just arrived hours before and found people sleeping everywhere like house cats when Muhammadu Buhari‘s army showed up to haul everyone to jail. Kuti was an opponent of the government who was in jail, and they came to arrest his coterie of supporters. They grabbed Goldman and were about to throw her in a truck until Pascal Imbert, Kuti’s manager, yelled out, “Leave her alone. She just arrived from Paris! She’s my wife! She knows nothing!

Goldman stops for a moment and then smiles plainly. “They thought I was just some stupid woman…. That time sexism worked in my favor.”

Vivien Goldman has become a living, teaching testimony of the golden era of punk and reggae. She is an adjunct professor at New York University who has taught courses on the music scene she was thrust in the middle of as a young public relations representative for Island Records. She writes a column for the BBC called “Ask the Punk Professor” where she extols the wisdom she gained as a confidant of Bob Marley; as the person who first put Flava Flav in video; as Chrissie Hynde‘s former roommate; as the woman who worked with the The Clash, Sex Pistols, The Slits and The Raincoats.

As Wikinews reporter David Shankbone found out, Goldman is one of those individuals that when you sit in her presence you realize she simply can not tell you everything she knows or has seen, either to protect the living or to respect the dead.

DS: The first biography of Bob Marley, Soul Rebel, Natural Mystic, was written by you based upon your personal experiences with him, and you have recently written a book about Marley called The Book of Exodus. How difficult is it to continue to mine his life? Is it difficult to come up with new angles?

VG: The original biography was written in a weekend and it was based upon my extensive interviews with him, whereas the Exodus book took two and a half years. I must have been a year past deadline, because it kept on growing. Even I had to acknowledge it was a more mature work. After I wrote the first one, all these other people came out with books. I read them, and they were all good in their different ways, but there was a story that had not been told but that I had lived so intensely, a deep story that had shaped my whole life. It demanded I write a book about it. Nobody else has the experience, and I still have that oompf.

DS: You were there with Marley through that time when he really caught on; was it obvious to you then that there was something amazing and unique happening?

VG: It was really something, and it was huge, but I didn’t examine it then. I believed in Bob with every fiber of my being, but it was hard to realize how everybody in the world would get it in the end, and just how towering a figure and enduring he would prove to be. He deserves everything and more; the role that he occupies is so central. It would have been hard to envisage how huge he became, though.

DS: Warhol’s Factory photographer, Billy Name, once told me he knew that what was going on was amazing, but he never thought Warhol would become the entire fabric of the art world as he is now.

VG: Especially in New York. Warhol was so associated with the punk scene.

DS: But Marley has become a fabric of sorts…

VG: Oh, he’s beyond the fabric of reggae, he’s the fabric of the rebel spirit. Now everybody just puts on a little red, green and gold and they feel it identifies them as being there in the struggle. Even if it is someone flying to the Hamptons for the weekend, they bring out Marley to expresses the rebel aspect they don’t want to completely lose.

DS: How do you define punk?

VG: There are two things. First, the aesthetic: harder, faster, louder. But the second thing is what interested me more, which was the rebel spirit and attitude. That free spirit of punk; that implicit sense of wanting to change a system that is always unfair wherever you are, except for maybe in the Netherlands. But it’s become so commodified

DS: What is the commodified version of punk selling?

VG: Edgy and dangerous. It is amazing: you open the New York Times and the free bits fall out and you get Urban Outfitters or Old Navy with lines of punk kiddie clothes. K-mart, even. I was trying to see what was so deeply punk about those clothes. They were maybe more colorful or something, but they weren’t punk. It’s like the Swarovski crystal take on punk, I mean, please!

DS: That aesthetic is everywhere, as though if one spikes his hair he is punk.

VG: Well, the punk is in the heart, to paraphrase Deee-Lite. I was writing about Good Charlotte and The Police. They adopted the trappings of punk. They aren’t bad groups, but the punk aspect is more manifested by somebody like Manu Chao. He’s one of the punkiest artists out there I can think of. It’s an inclusionary spirit that is punk.

DS: Your philosophy is that punk is not just musical, but also an aesthetic. That it can imbibe anything; that it stands for change and for changing a system. Let me give you a few names, and you to tell me how you think they are or are not punk. Britney Spears.

VG: Oh, no she’s not punk. Punk is not just about wearing smeary black eyeliner, but some sense of engagement. That’s it in a nutshell. She doesn’t have that sense of engagement. She is society.

DS: Dick Cheney.

VG: He is the essence of Babylonian, old structure capitalism, which is about greed and how much one can take for himself. I could see capitalism that is mutually beneficial, such as ‘I want a bigger customer base,’ but they don’t. Take a place I know well like Jamaica. I don’t know if you have seen that documentary Life and Debt, about how the INF squeezed everything out of Jamaica, but that’s a typical thing that happens. Instead of building these people up and paying them a living wage for their work, where we could sell more to them, we just want to suck everything out of the place. Suck the sugar, suck the labor. And that is not very punk. It’s the opposite of punk. That’s what Dick Cheney represents to me. He tries to bring about change, but change that just fattens his pocket. It’s not thinking of the community, and that’s what punk is about.

DS: Kanye West.

VG: He seems to be a positive force. In that sense, I would file him slightly under punk.

DS: Osama bin Laden.

VG: He thinks he is a punk, but he’s too destructive. If I was sitting in the madrassa in the desert chanting the Koran seven days a week, I’d think, yeah, he’s a punk. But I’m not, so I don’t.

DS: Is the definition of punk relative, then? He’s a Madrasah punk but not a Manhattan punk?

VG: Having said that, they would loathe punks, so I think we can safely say, not a punk.

DS: Pete Doherty.

VG: Oh yeah, I think he’s a punk. He’s a punk and he engages with the system in terms of how a powerful a presence he’s become. He is the Keith Richards of his day.

DS: If punk is about change, then why the maudlin sentimentality over the closing of CBGB‘s, which at times turned into demonizing a homeless shelter?

VG: Yeah, and they had not paid their rent, had they? I sided with the homeless shelter in a way, except I thought the whole thing was ridiculous because somebody should have stepped in and bought it and paid it and fixed it up, in the sense there is no shrine. They don’ think about the tourism, do they? I expect that of America now. Los Angeles just destroyed the Brown Derby, and the modernist architecture. That’s the thing about America. There seems to be very little regard for legacy. I think they should have kept CBGBs, but I think that more cynically. My students had a huge debate about it.

DS: I felt it was what it was at a certain moment, but it wasn’t that anymore. They were charging eight dollars for a beer. That’s not very punk, and that wasn’t attracting the punk crowds. It was like people who move to the Bowery because they think it’s so edgy but it’s really a boulevard of glittering condos.

VG: Nostalgie pour la boue: nostalgia for the mud. Not all of them, though. Patti Smith. Anyway, the spirit had moved on to Williamsburg.

DS: Where do you think New York’s culture is going? There are so few places on Earth with such a large concentration of creatives who meet and influence each other, but the city is becoming less affordable and cleansed of any grit. Is there a place for punk in the Manhattan of the future?

VG: They are flushing out the artists. Manhattan is now a ghetto for the very rich. When punk started it was in weird places, places you broke into and that had never been used for shows. It was never in regular venues, but now every nook and cranny is a regular venue and it doesn’t leave much space for the old punk spirit. ABC No Rio, I think they manage to work it in the system. And there are places like The Stone, John Zorn‘s place, which has avant-garde free form jazz. He subsidizes that place, so it remains a little haven. There are a few little pockets, but it has a lot do with the rent. Realistically, there’s loads of stuff happening in places like Brooklyn, more than there seems to be in Manhattan. When I jammed with The Slits, that happened at some after-hours thing in Brooklyn in some warehouse. I remember loads of things in funny places. The first time I heard Public Enemy I was on the rooftop of a building.

DS: You’re friends with Flava Flav, right?

VG: Yes, although I haven’t seen him in a very long time. I remember how I met him. I was doing this video for I Ain’t No Joke with Erik B and Rakim, and they weren’t very vibey in terms of the stagecraft, as it were. The projection. Not to diss anybody, but I needed someone to bring a bit more life into it; it was very low-budget, a vérité kind of shoot. We were in a playground in the projects and there were all these blokes hanging around, and there was one who was super-sprightly, like a live wire. I didn’t know it was Flava Flav and I shouted out, Hey, you, will you come over and be groovy for us? and he did and a lot of the action in the video is Flava Flav spinning around, doing a Dervish in the middle of the playground.

DS: At the time he wasn’t known?

VG: Well, it turned out he was in a group called Public Enemy. The first time I heard them was at a rooftop party, and it’s one of my great New York memories. It was a warehouse building that’s still there behind Houston and Bowery and I remember it was amazing because you never heard music like that before. It was blaring. It was so hot and we were in the middle of the city with graffiti on the walls, people smoking spliffs. It was very free. You don’t see that anymore. Everything is more heavily policed.

DS: Do you think apathy is a problem today?

VG: There’s less intelligent, critical content in general, and celebrity magazines pay the most and sell the most. It’s the Lowest Common Denominator. Britney Spears is an unbelievable example. She’s so young with no good guidance around her, and she is fodder for them to sell more magazines. There’s a gladiator aspect of it: the worse off she is, the better for that industry. But I’m still looking for the people who have conscience. Michael Franti, he’s one of the only ones I look to now. He had that band Spearhead. I’m looking around for conscious artists.

DS: What about G. G. Allin? He used to defecate on the stage to make a point.

VG: That’s quite extreme, and very unhygienic. I wouldn’t need to see that. I don’t think that’s necessarily punk, it’s just scatological. Some people might think it’s punk, but I personally wouldn’t dig it. It’s outrageous, but not in the way I find interesting.

DS: Well, he’s dead. Do you think people are afraid to speak out today?

VG: I guess in Vietnam you did, but now the culture isn’t nearly as organized.

DS: Is violence for the cause of social change punk?

VG: Violence will occur in social change. Violence has always been associated with punk, although punk wants peace in a way. When you look at all the bands in punk, like No Future and Blank Generation, it has implicit an aspiration to a place where you don’t have to be violent. Often it happens. The punk era was violent. Very, very violent. So many people were beaten up during those days. I’m very much a peacenik, but violence often happens, one observes, on the road to social change.

DS: Sandra Bernhard once did an homage to what she called the Big-Tittied Bitches of Rock n’ Roll: Heart, Joan Jett, Stevie Nicks. She mourned that there were no big-tittied bitches left. Who are the big-tittied bitches of Rock n’ Roll today?

VG: M.I.A. Tanya Stephens. Joan Jett, still. The Slits, who still suffer from the system and they are still brilliant. Male bands of that statute would have more deals. Big-tittied in terms of cojones, as opposed to cleavage as such.

DS: Do you have moments of extreme self-doubt where you wonder if anything you do matters to anyone?

VG: I have a lot of moments of extreme self-doubt, but you have to be humble and listen to what people say. Although I was never top of the New York Times book chart, I know people have liked my stuff, and that keeps me going. The classes have been amazing. I had done a lot of television and media, but it was the first time I had done something one-on-one. It was the old cliche that a person learns as much as they teach. Loads of my old students keep in touch with me; one wrote to me to tell me he is free-lancing for XXL and some other rap magazines, and how the classes really have been useful and he always refers to them. Even just one person is gratifying and encourages me to continue my work.

DS: You have worked for two corporations that are seen by many as the least punk in their respective communities, the BBC and NYU. How does one remain punk in such environments?

VG: I’m a freelancer. I go in, do my thing, and if they don’t like it then I don’t do it anymore. I stay true to myself, and if it doesn’t work out then I guess ‘fuck off’ on both sides. I haven’t had to compromise myself; nobody has asked me to. BBC America is a different animal than the BBC. As long as I can say what I want to say; I think people come to me because they know what they are getting.

DS: Have you ever been in a situation where you feared for your life, where you thought, this may be the way I go?

VG: There was a lot of violence in the punk times and I got beaten up in street brawls. I particularly remember once in Nigeria… I was there to make a documentary for Channel 4 about Fela Kuti. He was in jail at that time and he wanted to draw attention to his plight to showcase what was going on in Nigeria. It was hard to get through customs because my guides weren’t there to meet me. I found them hiding in the carpark because the police were after them.
We went to Fela’s house where I was going to stay; we went to the shrine and it was amazing. The whole house was covered in people sleeping. I was woken up by this little girl very early in the morning, only about two hours later. She was tapping me on the shoulder and when I looked around there was nobody there, whereas it had been covered in people. She said, “Come! Come! The army is here!”
I went outside and there was the army arresting everyone. People were lined up against the wall. Pascal Imbert, a French guy who was managing Fela, was already on the truck and they were about to take him away. There were all these really serious, heavey Nigerian soldiers with machine guns around. Not friendly, more like stone-faced Belsen guards. It was like that Bob Marley song Ambush in the Night: there were four guns aiming at me. They all turned their guns on me and said, “What should we do with her?” From the truck Pascal shouts out, “Leave her alone! She’s my wife! She’s just arrived from Paris! She doesn’t know anything!” The combination of the words “She’s my wife, she doesn’t’ know anything” were enough. Of course, I had neither arrived from Paris nor was his wife. But they just left me alone; they thought I was just some stupid woman. That time sexism worked in my favor. [Laughs] She doesn’t know anything! They were about to take Pascal away and I rushed up to the head guy very bravely—Pascal always gives me props for this—and I said, “Where are you taking my husband?!” They were actually taking him to a secret jail.

DS: What happened to him in the secret jail?

VG: There’s a documentary about it. He got very thin, he contracted dysentry and he got various diseases. No food, or terrible food. Luckily for him after some months there was an amnesty and he was amongst the prisoners who were released. That was a very heavy moment. I thought I would die, either right then or in a Nigerian jail.

DS: In Jamaica there was so much violence during the civil war.

VG: I’ve seen a lot of death. Many of the people I knew in Jamaica are dead. I think of them a lot; like my very, very close friend Massive Dread. He did so much for the community. At Christmas he’d hold a big party for the kids, and all the rival gangs would come. He was trying to break up some of the coke runnings. They started to have crack dens in Trenchtown and he worked against those. He was opening a library called the Trenchtown Reading Center, in the middle of this broken down ghetto, where kids could sit down to do homework and read books in this nice courtyard. It was really worthwhile.

Excellent Career Prospects With Online Holistic Medicine Courses

Excellent Career Prospects with Online Holistic Medicine Courses


Amit Kothiyal

Are you really planning to head start your career in the field of holistic medicine? If yes, then you have made an excellent choice. A degree program in holistic or alternative medicine is in high demand among the students and the best thing here is that it is associated with a successful career and high pay package. There are many career paths that you can pursue with this program such as Massage therapist, homeopathic practitioner, acupuncturist, yoga instructor and many other related professions. With plenty of jobs and opportunities, a career in this field is highly rewarding.

If you want to become a successful Doctor of Holistic Medicine (H.M.D.), then it is imperative that you attend a top school of holistic medicines. There are chances that you may put off the dream of starting a career in this particular field in a cold baggage largely because of your full time employment. Do not get disheartened as there are many best alternative medicine colleges that will make your dream happen. You must not take any stress because through the online courses, you will get quality knowledge and information from the experienced and professional mentors who will work to the best of their potential to provide the excellent skills.

Online Holistic Medicine Courses and Degrees

Today, there is no dearth of best online alternative medicine colleges that are worth considering. What is important here is that you undertake some research work to choose a program that will suit your needs and goals. The

Doctor of Holistic Medicine course

is essentially a 1.5 year post-graduate course. The course is classified into the two semesters of nine months. It is important that the students must make it a point to attend the semesters and complete the course so that they can enrich their career in the healthcare sector. Here are the various topics that are an essential part of the course and will put the students in a front seat:

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History, philosophy and principles of holistic health and living

Anatomy and physiology

Methods of nature care

Natural dietetics and nutrition

Gynaecology, embryology and maternity

Clinical diagnosis

Botanical / herbal medicine


Therefore, if you are aspiring to become a holistic medicine doctor, then you are certainly on the right path. It is pivotal that you must not forget to select the right online holistic medicine college and course to boost your career prospects and enjoy a rewarding future.

Indian Board of Alternative Medicines – IBAM (Established 1991) is one of the oldest and finest college of holistic medicine offering regular, correspondence and online

degree in alternative medicines

for both students from within India and worldwide. IBAM is a Government Registered Institution, also accredited in U.S.A., U.K. (Europe), Australia and New Zealand and internationally affiliated with I.A.E.W.P An Affiliate of the United Nations, UNICEF and UNESCO.

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Fifteen flu sufferers die in Wales in one week

Friday, January 14, 2011

Over the course of the last week, fifteen people who have suffered from influenza have died in Wales, as reported to the Welsh Assembly Government. The total amount of flu-related deaths in Wales since October 2010 has now increased to 27.

Despite the slight increase in the clinical consultation rate for influenza this week compared to the previous week, the rate of consultations for flu-like illness in Wales still remains within the levels of normal seasonal flu activity.

On Tuesday, 49 people were being treated in critical care beds in hospitals around Wales, according to health officials. With twelve reported admissions, Aneurin Bevan Local Health Board had the highest amount of critical care patients in Wales. Betsi Cadwaladr University Local Health Board has the second highest total number of patients experiencing this critical care in the country, with eleven being cared for. Cardiff and Vale University Health Board and Abertawe Bro Morgannwg University Health Board have nine important care admissions each. Cwm Taf NHS Trust contains five of such patients, while Hywel Dda NHS Trust has three.

The age group of 25–34 years old had the largest amount of meetings with general practitioners; the rate of consultation was 147 people for every 100,000. For all age groups, 93 people out of every one hundred thousand have been consulting with a GP; on January 5, the total figure stood at 85 meetings per 100,000.

“Despite the slight increase in the clinical consultation rate for influenza this week compared to the previous week, the rate of consultations for flu-like illness in Wales still remains within the levels of normal seasonal flu activity,” said Dr. Tony Jowell, the Chief Medical Officer of Wales. “Most healthy people will recover from flu-like illnesses within five to seven days with plenty of rest and drinking non-alcoholic fluids. On the issue of vaccination against seasonal flu, whilst we have been working to make stocks of the vaccine that was developed against swine flu available to be used where supplies of seasonal flu vaccine have run low, we are now well into the flu season.”

According to Media Wales, 13 patients experiencing flu-related symptoms were getting treatment at Withybush General Hospital in Haverfordwest on Tuesday. Meanwhile, five were receiving hospital treatment at Bronglais General Hospital in Aberystwyth. Also, Carmarthenshire NHS Trust in Llanelli and West Wales General Hospital in Carmarthen both had a solitary patient.

Jowell also commented: “People in at-risk groups are at a higher risk of complications from seasonal flu, and the best protection is early vaccination. A press and publicity campaign has been running since October and has included television, radio and bus adverts to let people know if they are in an at-risk group, and that the vaccine is available free of charge to those groups from GPs. We have also encouraged health boards and GPs to ensure that their patients and front line NHS staff are vaccinated against seasonal flu.”

Throughout the United Kingdom, 62 individuals reportedly died in the last week, as the result of suffering from influenza. The majority of these victims were suffering from swine flu. In most of these cases, the sufferers were aged between 15 and 64. However, nine of the fatalities were of children aged below fourteen.

‘Fascinating’ and ‘provocative’ research examines genetic elements of bipolar, schizophrenia

Saturday, October 1, 2011

Last week, Nature Genetics carried twin studies into the genetics of bipolar disorder and schizophrenia. This special report examines the month’s research into the illnesses in detail, with Wikinews obtaining comment from experts based in Australia, the United States, and the United Kingdom ahead of the U.S. Mental Illness Awareness Week, which starts tomorrow.

Eleven genetic regions were identified; seven of these were for schizophrenia and five of those were hitherto undiscovered. The parallel studies, conducted separately, examined more than 50,000 people worldwide and identified two genetic loci associated with both diseases.

Little is known about the two illnesses, each of which affects around 1% of people and is treated with strong medication. Bipolar sufferers experience extremes of mood – depression and mania, hence the previous name “manic depression” for the illness. Schizophrenia is associated with hearing voices, chaotic thoughts, and paranoia. There is no known cure.

The latest research examined both the healthy and the afflicted, using computers to scan genomes. Inheritance was thought to be a factor from prior knowledge of the diseases as a familial trait, but the original desire had been to isolate a single faulty gene. Instead it has become apparent that the genetic factors are many; in the case of schizophrenia, at most around 30% of the genetic components are thought to have been identified.

If any single centre tried to undertake such a study, it would require millions of pounds.

The University of Chicago’s Pablo Gejman, a lead researcher on the schizophrenia study, explained to Wikinews in a telephone interview from Buenos Aires, Argentina that “One of the goals of genetic research is to find druggable targets” – to “find treatments at the root of the problem”.

Whilst noting that there is no guarantee the genetic code identified is druggable, Gejman named calcium-activated neurochemical channels in the brain as candidates for new drugs. The channels were linked to schizophrenia in the study.

Gejman explained that a genetic locus called mir137 “suggests an abnormality of gene regulation.” The diseases are so poorly understood that it is uncertain if they are in fact two components of a single spectrum, or even each comprised of multiple illnesses.

The new and “provocative data” gathered showed the significant loci identified were “not part of the pre-existent hypothesis.” Calling this “interesting”, Gejman added that the team found no evidence that dopamine receptors are involved; current drug treatments target dopamine receptors. The findings are “not related to anything we thought we knew [about schizophrenia],” he told our correspondent.

Quizzed about the possibility variations in the genetic factors involved in expressing the diseases explained the variation seen in symptoms, Gejman was uncertain. “We will have the answer, probably, only when we sequence the whole [human] genome.” He notes that the relationship between genotype and phenotype is unclear, and that “We know very little of the genetic architecture of schizophrenia and” other disorders. At the time the results were published, participating scientist Professor Rodney Scott from the University of Newcastle in Australia said “The strength of this research is in the numbers. The findings are robust and give us a lot of statistical power to identify the genetic determinants of schizophrenia.” Scott told Wikinews that “If any single centre tried to undertake such a study, it would require millions of pounds. Since it was a collection of data from across the world the costs were spread. In this era of financial difficulty it will become increasingly difficult to secure funding for this type of project even though the pay-offs will be significant.”

Gejman expressed similar sentiment. “The research budget is not growing, which makes [funding] difficult,” he said, though he felt the cost “is not prohibitive because of the benefits.” “I think that it was money well invested” and “very well spent for the future,” he said, adding that organisations in Europe and the US were aware of the importance of such research.

Gejman also agreed on reliability – the study is “Very reliable because of the sample size; that should provide robust results… [we] have worked with a much larger sample than before.” Scott told us it was “a highly reliable study” that has the potential to lead to new treatments “in the long run”.

Another point was the two genetic loci identified as common to both – how much support do they lend to the notion the diseases are linked? “Until more information is available it is really only suggestive,” says Scott. “Strong enough to say there may be potentially a common pathway that bifurcates to give rise to two diseases.”

The provision of specialist services for bipolar is very limited in the UK and the demand for our services is unprecedented.

“It is an excellent demonstration,” said Gejman “because you have the same chains that are common to both disorders, in fact not just the same chains but also the same alleles.” He stressed uncertainty in how strong the relationship was, however.

Scott said examining how the variation of genetic factors may translate into varied symptoms being expressed “certainly is a good target for future research”; “It is not known how many genetic factors contribute to either of these diseases but it is likely that not all are necessary to trigger disease.” “New questions will always arise from any major study,” he told our reporter. “Certainly, new questions about bipolar and schizophrenia are now able to be formulated on the basis of the results presented in the two reports.”

These weren’t the only studies to look at the two diseases together in September. The British Medical Journal carried research by a team from the University of Oxford and King’s College London that examined mortality rates in England for schizophrenia and bipolar sufferers. They found both groups continued to suffer higher mortality rates than the general population – whilst these included suicides, three quarters of deaths were down to ailments such a s heart conditions. General death rates dropped from 1999 to 2006, but sufferers below 65 saw their death rate remain stable – and the over-65 saw theirs increase.

“By 2006, the excess risk in these groups had risk to twice the rate of the general population, whereas prior to that it had only been 1.6 times the risk, so it increased by almost 40%,” said Dr Uy Hoang of Oxford. The study looked at every discharged inpatient with a diagnosis of either condition in England in the relevant time.

Hoang said at the time of the research’s release that doctors should devote attention to predicting and preventing physical illness associated with mental disorders. His study comes at a time when the UK has launched a “no health without mental health” strategy which does attempt to screen for physical illnesses coinciding with mental illnesses. The government aims to reduce the death rate of those with mental disorders.

Rodney Scott described this research result to Wikinews as “Possibly” connected to genetic association with other hereditary ailments, such as cardiovascular disease; he told us another possibility is that “The continued raised mortality rates may be associated with the diseases themselves.”

“We believe the NHS [National Health Service] and Department of Health need to do more to support research and service development for people with bipolar disorder,” Wikinews was told by Suzanne Hudson, Chief Executive of London-based British charity MDF The Bipolar Organisation. “The provision of specialist services for bipolar is very limited in the UK and the demand for our services is unprecedented.”

“A genetic test for bipolar would be a useful tool but the science and ethics are very complex,” Hudson told us, referring to the Nature Genetics genetic study. “Just because someone has ‘bipolar genes’ does not mean they might go on to develop it. Family studies of bipolar show that this is a likely outcome of genetics research in this area. Even if it were possible to accurately predict bipolar in this way, questions about how you treat that person are difficult. For example do you start medication that is not necessary at that point in time?”

“Current treatment is not satisfactory” because it does not always work and has “side effects,” Gejman told us. Robert Whitaker, a US medical journalist and book author, told an audience in New Zealand at the end of August that evidence suggests antidepressant drugs may make children and teenagers worse – “You see many become worse and end up with a more severe diagnosis, like bipolar illness,” and the suicide risk may increase.

Whitaker blames commercial interests. “The adult market appeared saturated, and so they began eying children and teenagers. Prior to this, few children and youth were seen as suffering from major depression, and so few were prescribed anti-depressants.”

One possible alternative, raised by a connection between depressive illness and inflammation, is aspirin and similar compounds. “The link between inflammation and mood disorders has been known for sometime and the use of aspirin and other drugs in depression is now becoming more common in the literature,” Hudson says. “Any new treatments for bipolar, which is a very complex and co-morbid illness, has to be a good thing.”

Professor Dr. Michael Berk, chairman of psychiatry at Australia’s Deakin University, recently gave a talk to just this effect. Speaking at this year’s Congress of the European College of Neuropsychopharmacology, held this past month, he also highlighted statins as a treatment. Recognising the link to physical ailments, he told an interviewer “The brain does not exist in isolation, and we need to understand that pathways similar to those that underpin risks for cardiovascular disorders, stroke, and osteoporosis might also underpin the risk for psychiatric disorders, and that other treatments might be helpful.”

Berk also touched upon speed of diagnosis and treatment; “Early interventions can potentially improve the outcome” of bipolar sufferers, he told his audience. MDF The Bipolar Organisation claim an average of ten years is possible before a person is diagnosed. “This clearly is an issue, if we believe that earlier diagnosis and treatment facilitate better outcomes,” Berk told Wikinews. Though he questions the effectiveness of currently-used drugs on advanced bipolar cases, he does not go so far as to say drugs are actively harmful. He told us “it appears that our best treatments work best earlier in the illness course; and that seems to apply to psychotherapy and pharmacotherapy.”

Berk has already performed research using statins which suggests they can form a treatment. He now seeks funding for research involving aspirin. On funding, he tells Wikinews “psychiatric disorders comprise between 16% and 22% of the burden of disability (depending on who measures it), attracts[sic] just over 6% of the clinical budget at least in Australia and 3% of the research budget. Research as a discretionary spending item is at great risk.”

Berk’s research, in the past, has been funded by companies including GlaxoSmithKline. Hudson told Wikinews this did not concern her charity; in fact, they welcomed it. “We believe it is important pharmaceutical companies continue to invest in the development of new medications for bipolar. This is how it works in all other health specialities and mental health should be no different.”

“There is a need for greater education for mental health professionals and GPs [general practitioners] about bipolar [in the UK],” she told us. “As the national bipolar charity we receive many, many calls and requests from GPs and other health professionals for our leaflets and information sheets which is fantastic. We very much welcome opportunities to work together for the benefit of individuals affected by bipolar.”

Wikinews contacted the UK’s National Institute for Clinical Excellence (NICE) to discuss issues raised in this article, including future treatments, genetic screening, and mortality rates. NICE did not respond.

Might statins and/or aspirin improve treatment – might they be cheaper, perhaps, or safer? “This is an area of research promise,” says Berk, “however it is too early to make any clinical treatment claims; [all] we can say is that this needs to be studied in properly designed trials capable of giving a more definitive answer.” And what of possible explanations for the increased mortality rate observed in England? Should researchers look at whether bipolar influences more than just the brain, or if it is linked to other genetic conditions?

“For sure,” he told us. “There is new evidence that similar pathways contribute to the risk for both medical and psychiatric illness, both in terms of lifestyle factors, and biomarkers of risk.”

MDF The Bipolar Organisation provide support to those with bipolar and their friends and family: 020 7931 6480

Britain unveils flu pandemic preparedness plan, buys 14m courses of treatment drug

Tuesday, March 1, 2005

The government of the United Kingdom has unveiled their strategy to deal with any future influenza pandemic in their Pandemic Influenza Contingency Plan.

The document, based on the World Health Organization‘s framework for responses, explains how the UK would respond to a major outbreak of flu.

Any flu pandemic would differ from the seasonal outbreaks of flu observed worldwide every year. While seasonal flu kills 12,000 Britons annually, a pandemic would affect far more people and could result in the deaths of up to 50,000 people in the UK if there were no medical intervention.

The government will have the power to cancel events where large numbers of people gather, such as football (soccer) matches. It could also advise travel restrictions to and from areas of high infection, but would not be able to enforce any such measures.

Schools might be closed in the event of a flu pandemic, and infected people would be asked to remain at home, although again no quarantine measures could be imposed by the government.

Further plans include education of the public to recognize symptoms of the flu and how to avoid infection.

Measures will be made to maintain basic services in the event of a pandemic despite staff absences through illness.

A major cornerstone of the plan is the prescription of oseltamivir, an oral neuraminidase inhibitor drug that combats influenza. The drug is currently marketed by Hoffman La Roche under the trade name Tamiflu®.

The UK Department of Health intends to stockpile 14.6m courses of the drug over the next two financial years, giving enough to treat one in four of the population – the ratio recommended by the WHO.

Canada and Australia have also bought the equivalent amounts of anti-viral drugs. The U.S. has also bought large amounts of similar drugs.

The total cost of the acquisition was not published by the government, but the BBC estimated the cost to be £180 million.

Unlike a vaccine, oseltamivir can be used to treat any strain of the influenza virus. Many new variants of the influenza virus are seen every year, and combined with the long lead times associated with the development of vaccinces, mass vaccination is frequently impractical.

Some parts of the newly-revealed plan already exist. The UK government recently gave £500,000 to the WHO for survellience of so-called ‘bird flu’ in South East Asia, a possible source for any future pandemic. The Department of Health will also continue to monitor flu-like cases seen by doctors and hospitals.

Carhartt Bib Overalls For Every Worker: The Only Choice}

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Submitted by: Jem Jamey

Buying Carhartt bib overalls is not just like buying your regular jeans. Thats because you buy Carhartt bib overalls to get rugged and durable work clothes. And easiest part about it though is you wont have to look hard. You only have find where Carhartt bib overalls are and find your size.

Carhartt Bib Overalls: When Do You Need Them?

Certain jobs require protection. Whether you are just doing a personal project or you do such jobs for a living, getting Carhartt bib overalls is something you just have to do. Avoiding soot and dirt is achieved when you wear Carhartt bib overalls. Quilted Carhartt bib overalls would also provide insulation and warmth to the workers.

Well, all Carhartt bib overalls are made from the most durable and toughest materials. But the design of each type of Carhartt bib overalls is different to fit the requirements of every type of worker wearing them.

Carhartt Bib Overalls: Mens Duck Zip to Thigh

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This type of Carhartt bib overalls is made of 100% cotton duck. It is zipped from the ankle up to the thigh. This makes it easy for you to put on and to strip off every time you use it. It also features hammer loops on both sides.

This Carhartt bib overalls style offer more protection with the double knee feature. This way knee pads can be used by every worker when they need to. Less injury would be incurred. Doing the job would also be easier.

The Mens Duck Zip to Thigh Carhartt Bib Overalls also has elastic suspenders to give a good fit. You can be sure that back pockets are reinforced too. There are also several pockets to accommodate your other tools.

Most of all, this Carhartt Bib Overalls will protect you from the wind. It will protect your clothes as well.

Carhartt Bib Overalls: Mens Duck Carpenter Style

This style is also made from the same heavyweight 100% cotton duck. It also has hammer loops on it and multiple pockets. It features the reinforced back pockets. The only main difference is that the mens duck carpenter style has an attached nail apron. Its specifically made for the carpenters or for people who are going to do some fixing and hammering.

Carhartt Bib Overalls: Mens Sandstone Style

Like the other Carhartt Bib Overalls styles, featured are the reinforced back pockets. It has multiple pockets and hammer loops. The double knee feature is, of course, also present. An additional feature though is the brush loop. There is also a tool pocket on the right leg and a ruler pocket on the left side.

Each leg has a zipper that opens up to the knees. It also has a protective wind flap. So the mens sandstone Carhartt Bib Overalls is really functional. It does not only give you protection but it actually makes doing your job easier and faster.

You would have a choice between the lined Sandstone Carhartt Bib Overalls and the unlined one. The lined Carhartt sandstone overalls are made of 100% nylon quilt and it has a midweight lining as well. But it still has elastic suspenders.

Carhartt Insulated Bib Overalls

It still offers the same features as the other Carhartt Bib Overalls. But a unique feature to this type is the zip fly. It also has coin pockets. The most important feature of the Carhartt insulated bib overalls though is its being water repellant.

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President Bush may veto amendment that bans detainee mistreatment

Saturday, October 8, 2005

The first veto of United States President George W. Bush’s presidency may be used to block an amendment that bans torture and mistreatment of detainees, proposed by two Republican senators. The White House sent a “statement of administration policy” to the Senate declaring strong opposition to the legislation, alleging that it would tie the nation’s hands in the “War on Terrorism”. The statement said that if the bill’s final version contained the anti-torture terms, then “the president’s senior advisers would recommend that he veto the bill.”

The amendment, an addition to the $440 billion dollar military spending bill, proposed by senators John McCain and Lindsey Graham, would establish the Army Field Manual as the uniform standard for the interrogation of Department of Defense detainees and secondly prohibit cruel, inhuman, and degrading treatment of persons detained by the U.S. government.[1]

The legislation comes in the wake of the Abu Ghraib prison abuse scandal and allegations of Human Rights Watch, which, in a recent report, accused soldiers of the U.S. Army’s 82nd Airborne Division of “systematically torturing Iraqi detainees”. The report was critizised by a Department of Defense spokesman as using “distortions and errors in fact.”

The amendment received 90 votes in support, and 9 votes against in the Senate. Former Secretary of State Colin Powell, as well as 28 other retired senior military officers, also endorsed it.

General Powell said in a letter to McCain: “Our troops need to hear from the Congress, which has an obligation to speak to such matters. I also believe the world will note that America is making a clear statement with respect to the expected future behavior of our soldiers.” Powell said the Senate action “will help deal with the terrible public diplomacy crisis created by Abu Ghraib.”

McCain, a one-time P.O.W. during his military service in the Vietnam War, said after the vote that the White House should not be working against him on this issue: “We think it would be very helpful because it would send a message to the world that the United States of America does not engage in torture. We will not treat people inhumanely. We will adhere to treaties that we are signatories to, and the men and women who do the interrogating will have clear instructions as to how to conduct interrogations.”

Senate Majority Leader Bill Frist, who later voted for the bill, and White House lobbyists led the unsuccessful opposition to the amendment and senator Ted Stevens had argued that the amendment would prevent “our people from taking the leadership. (sic)”